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1920 S. Kingshighway Blvd.
St. Louis, MO 63110

API Manufacturing Expansion

July 9, 2019

McGrath fully coordinated the design and construction of a new, $32 million greenfield Active Pharmaceutical Ingredient (API) manufacturing plant. The project was “turn-key”, with McGrath providing design, procurement, construction, instrument pre-commissioning and commissioning services for the new API production facility. McGrath managed all process equipment procurement, coordination and FAT / SAT processes. This project included blast wall construction and deflagration venting. The project included filter dryers, centrifuges, stainless steel reactors, and other process equipment. Work [...]

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Biologics Production Expansion

McGrath is the construction manager on a $50 million site expansion, McGrath performed concept budget estimating on the 66,000-square-foot project. This is a fast-track project that will have gone from design kick off to commissioned suite in 14 months. Expansion will allow site to have second largest base of single use bio reactors at a contract development and manufacturing organization (CMO) in the world. Expansion will add 16,000 L of single-use bioreactor volume. The expansion [...]

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ADC cGMP Commercial Facility

McGrath fully coordinated the Design and Construction of a new ~ 10,900 sf cGMP manufacturing suite inside an operational, multi-product drug conjugate facility. The $11 million project was “turn-key”, with McGrath providing design, procurement, and construction of the new flexible multi product suite. The process involved linking a highly potent compound to antibody in an ADC reactor. The construction involved the build out of a shell space for the new facility with ISO 7 and [...]

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API Production Renovation

This $5.3 million project consists of the relocation of an existing process. CE&IC & McGrath provided the Design and Construction Services to renovate the existing Production Area. This project included the purchase and installation of glass line reactors, stainless steel formulation tanks, pressure canisters and PTFE lined receivers, heat exchangers and condensing units at the facility. Piping systems included stainless steel WFI and USP water piping and Teflon lined carbon steel process piping. New heat [...]

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BSL1/BSL2 Lab Expansion

This project consisted of the 44,400 sf renovation of an existing area on the first floor of the building. Areas specific to this project include BSL1 and BSL2 Labs, Quality Labs, Packaging Rooms, Freezers, Coolers and Support spaces. Additionally, staff restrooms and cubicle areas were constructed. This $8.5 million project consisted of approximately 7,000 sf of Cubicles, Break Rooms, Conference Rooms, Offices, and Copy Areas. McGrath worked closely with POE to deliver and install all [...]

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